Another large study conducted in 9360 women not only found that the prevalence of NAFLD increased in parallel with increasing age, but also that the prevalence rates of NASH (assessed with a BMI/age/alanine aminotransferase (ALT)/triglyceride (BAAT) index ≥3) were 13.2% vs. 14.9% in women >55 years and obese women with NAFLD, respectively, thus suggesting that post-menopausal age and obesity exert almost the same adverse impact on the risk of developing NASH [105]. This evidence concerns the gene GPT and obesity due to melanocortin 4 receptor deficiency.