Preliminary evidence also suggests some benefit of pioglitazone in the treatment of women with PCOS [20,44], as well as the use of either liraglutide or other glucagon-like peptide-1 receptor agonists for decreasing intra-hepatic fat content and visceral adipose tissue among women with PCOS who exhibit overweight/obesity [45,46]. The gene discussed is GLP1R; the disease is polycystic ovary syndrome.