The PLRM using data from the day of ARDS diagnosis found that DAD (OR 2.296 [1.228–4.294]; p < 0.001), diabetes mellitus requiring insulin (OR 0.081 [0.009–0.710]; p = 0.023) and respiratory rate (OR 1.045 [1.001–1.091; p = 0.046] were independently associated with mortality (Table 5). This evidence concerns the gene INS and acute respiratory distress syndrome.