This analysis led us to select the following SNPs: rs2910164 C/G in miR-146a, rs4597342 T/C in the 3'UTR of ITGAM, rs1368439 G/T in the 3'UTR of IL12B and rs1468488 C/T in 3'UTR of IL17RA. The majority of other genes involved in psoriasis inflammation rarely exhibit polymorphisms in the 3'UTR or the change in the Gibbs-free energy due to the polymorphism is low. Here, IL12B is linked to psoriasis.