Notably, VEGF‐C is an important binding ligand for NRP–2.23 Studies have indicated that the VEGF‐C/NRP–2 pathway was involved in promoting survival of prostate carcinoma cells under chemotherapy‐induced stress by activating autophagy.24 However, the effect of VEGF‐C on cell death and autophagy in renal epithelial cells has not been previously examined. The gene discussed is VEGFC; the disease is prostate carcinoma.