Also, it was found that transcripts of DRB5*0101 allele were more common in all tissues; accordingly, DRB5*0101 and DRB1*1501 expression were at substantial and largely comparable levels on the surface of various cells; also their expression was similarly modulated upon activation of B cells and monocytes by interleukin-4 (IL-4).3 Furthermore, in a study on Brazilian patients with MS, overrepresentation of DRB5 was reported.18,26. The gene discussed is HLA-DRB1; the disease is myeloid sarcoma.