Using the model of atherosclerosis in mice or the apolipoprotein E-deficient mice, Rosenblat et al. [83] reported that liposomal coated GSH in a dose of 50 mg/kg/day for two months showed significant reduction in serum susceptibility of 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH) oxidation, in a correlation with an increased level of GSH content in peritoneal macrophages, reduction in lipid peroxides [83], and also a decrease of the extent of oxidized LDL. Here, APOE is linked to atherosclerosis.