To estimate the ovarian antioxidant potential, TAC,MDA, SOD and CSG-px levels were analyzed.Observations showed significant (P<0.05) reduction inTAC, SOD and GSH-px levels of ovaries in the PCOS-sole group versus the control animals, while, ovarianMDA content was increased in the PCOS-sole groupscompared to the control group. The gene discussed is SOD1; the disease is polycystic ovary syndrome.