TNF and capillary leak syndrome: Indeed, in limited prior screening of acute SCLS sera, we found elevated levels of pro‐inflammatory mediators including TNFα, CXCL10, CCL2 and IL‐8.2, 3 To more fully probe the SCLS proteome, we performed SOMAscan profiling of 1305 proteins in nine matched plasma samples obtained by venipuncture during acute or convalescent intervals.