All glioma patients received operative intervention (mean resection rate was 95%), and chemoradiotherapy and chemotherapy with temozolomide according to the NCCN regimen.23, 24, 25 The major factors such as sex, age, Ki‐67, and glioma grade were investigated(low‐grade glioma (WHO grade II) and high‐grade glioma (WHO grade III‐ IV). The gene discussed is MKI67; the disease is central nervous system cancer.