In addition, the separation of HER2-enriched cancers was successful, yielding the following accuracies: HER2-enriched vs. luminal A, 80.4 % (Fisher/based on COM features); HER2-enriched vs. TN, 81.3 % (POE + ACC/based on COM features); and HER2-enriched vs. all others, 81 % (MI/based on COM features). Here, ERBB2 is linked to cancer.