To further analyze the relationship between Cav-1 and Pofut1 in HCC, two cell lines differing in Cav-1 expression and relative metastatic potential were selected: the poorly metastatic Cav-1-null cell line Hepa1-6 and the highly metastatic Cav-1-expressing HcaF cell line; Hca-F cells exhibit much higher metastatic potential than do Hepa1-6 cells (80% vs 0%)8. Here, CAV1 is linked to hepatocellular carcinoma.