The result showed that NR4A3 mRNA levels in clinical BC tissues (N = 15) is significantly lower than the normal breast tissues (N = 15) (Fig. 4e) and that the mRNA level of NR4A3 was reversely correlated with the expression levels of miR-665 in these samples (R = −0.4147, P = 0.001) (Fig. 4f). Here, NR4A3 is linked to breast cancer.