FMRP has been shown to bind to the GABAAR δ-subunit (Miyashiro et al., 2003; Dictenberg et al., 2008) and Fmrp knock-out reduces δ-subunit mRNA and protein expression in the amygdala, cerebellum, cortex, and dentate gyrus (DG) of a mouse model of FXS (D’Hulst et al., 2006; Curia et al., 2009; Braat et al., 2015; Zhang et al., 2017). The gene discussed is FMR1; the disease is fragile X syndrome.