Thus, we conducted a case-controlled study in a Chinese Han population and found that the RANK gene rs1805034 polymorphism was not related to RA risk; this was consistent with Assmann et al. [12] but not with Mohamed et al. [9] There are several possible reasons for these different findings regarding the rs1805034 polymorphism. This evidence concerns the gene TNFRSF11A and rheumatoid arthritis.