On comparing CRP and PV it was found that CRP had a higher AUC for infection (AUC 0.638, 95% CI = 0.608 to 0.670 versus 0.597, 95% CI = 0.564 to 0.628, P = 0.004 [Table 4]), with no difference for cancer (P = 0.49) or autoimmune disease (P = 0.97). This evidence concerns the gene CRP and acquired polycythemia vera.