We did not identify which cells in the stromal tumor-infiltrating lymphocytes were positive for PD-L1, but even though tumor-associated macrophages were the predominant PD-L1-positive cells in our results, it is difficult to explain the result because it has been known that PD-L1-expressing tumor-associated macrophages contribute to an immunosuppressive tumor microenvironment via inhibition of T cell proliferation and induction of T cell apoptosis to help tumor growth [17, 18]. The gene discussed is CD274; the disease is neoplasm.