Otherwise, carcinomas classified as Neo-Bioscore = 6–7 (9.0%; 28/310) prevailed in postmenopausal status (64.3%; 18/28), histological grade III (100%; 28/28), negative ER (75.0%; 21/28), Ki-67 ≥ 20% (92.9%; 26/28), negative HER2 (89.3%; 25/28), TN subtype (57.1%; 16/28), size T3/T4 (100%; 28/28), positive axilla (96.4%; 27/28) and stage III (100%; 28/28) (Table 1). Here, ESR1 is linked to carcinoma.