Most of the carcinomas had Neo-Bioscore ≤5 (91.0%; 282/310) with histological grade I/II (56.7%; 160/282), positive ER (61.0%; 172/282), Ki-67 < 50% (70.2%; 198/282), negative HER2 (74.8%; 211/282), non-TN subtype (72.3%; 204/282), size T3/T4 (60.6%; 171/282), node-positive axilla (71.2%; 201/282) and stage III (62.1%; 175/282). Here, ESR1 is linked to carcinoma.