ESR1 and carcinoma: Otherwise, the non-pCR carcinoma presented similar clinical characteristics to pCR carcinoma with size T3/T4 (63.3%), axilla N1 (43.8%) and stage III (62.9%) but different biological factors with histological grade I/II (53.9%), ER Allred 7–8 (49.4%), Ki-67 < 50% (71.5%) and Luminal B (30.3%) (Table 1).