In order to explore the genetic bases of the MLL-rearranged (MLL-R) ALL, in 2015 Andersson et al. conducted WGS, WES, RNA-seq and targeted sequencing of 67 MLL-R cases (47 MLL-R infants and 20 older children) and 18 non–MLL-R cases [65]. This evidence concerns the gene KMT2A and acute lymphoblastic leukemia.