Thus, both miRNAs target similar genes and regulate related pathways, such as the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20), a negative regulator of the NF-κB pathway [45] that has been previously associated with liver fibrosis and inflammation in an HCV infection [46]. This evidence concerns the gene TNFAIP3 and Hepatic fibrosis.