Four genes, C2, CFB, MBL2, and SERPINA1 (p: 0.00055) were found effective in complement and coagulation cascade on the immune system, three genes, C2, CFB, MBL2 (p: 0.008) were found effective in staphylococcus aureus infection and three genes, ATP6V0A4; CLEC7A, MBL2 (p: 0.05) were found effective in the occurrence of cellular phagocytosis and there was an association between mutations and Rb in the study. This evidence concerns the gene CLEC7A and staphylococcus aureus infection.