IL1B and Sepsis: SOFA score reflects the facets of organ dysfunction; therefore, the sepsis patients with high SOFA score might have more severe organ dysfunction, which contributed to the undesirable survival.16, 17 Additionally, IL‐1β was a well‐known proinflammatory cytokine; therefore, the high expression of IL‐1β might lead to the activation of the inflammasome response, as well as predict the worse survival in sepsis patients.18