In the primary hepatic cancer group (group A), an increased AFP level above the cut off level was observed in 681 study subjects accounting for 63.35% of the PHC patients; 83 subjects had increased AFP and CEA levels (7.7%); 78 subjects had increased AFP and CA19-9 levels (7.3%); and 27 subjects had increased levels of AFP, CA19-9 and CEA (2.5%). This evidence concerns the gene AFP and liver cancer.