Several of these hits including cg18181703 (SOCS3), cg06126421 (TUBB), and cg05575921 (AHRR) were associated with future incidence of coronary heart disease and smoking [13], whereas two other CpGs were recently identified in an EWAS of type 2 diabetes [41]. The gene discussed is SOCS3; the disease is type 2 diabetes mellitus.