One recent meta-analysis involving 3674 patients from 18 trials evaluating the correlation between PD-L1 expression in TIICs and the survival of cancer patients suggested PD-L1 positive expression on TIICs was correlated to a lower risk of death (HR = 0.784, 95% CI: 0.616–0.997, P = 0.047) [95]. The gene discussed is CD274; the disease is cancer.