Due to the important role of the adenosinergic pathway in the suppression of the antitumor immune response [14, 41–43], its clinical relevance as a therapeutic target to several tumors, and the fact that CD73 expression in cervical cancer cells has been associated with increased metastatic potential [54], it would be interesting to repeat these experiments using a larger number of cervical samples from both patients with CIN-1 presenting infection with both low- and high-risk HPVs and including other lesional tissues, such as CIN-3 and cervical cancer. Here, NT5E is linked to infection.