We earlier showed that COX-2 is almost exclusively expressed by HCMV-infected cells in medulloblastoma and that COX-2 inhibition acts to inhibit HCMV, which led to decreased tumor growth in an animal model (Baryawno et al. 2011; Schroer and Shenk 2008). The gene discussed is PTGS2; the disease is medulloblastoma.