The extent of CD62P expression was lower in a tube, which first had a mild agonist stimulation, and it was then treated with a high dosage of ADP than a tube which was solely treated with a high dosage of ADP, and thus it can be concluded that platelets decreased the response to agonist under the effect of desensitization phenomenon that could help platelets that were constantly exposed to agonist in a diabetes metabolic environment [28]. Here, SELP is linked to diabetes mellitus.