To further analyze the reliability of these six factors (CCL5, MIP-1β, HA, LN, PC-III and C-IV) within and between the two groups, CHB and HBV-related cirrhosis group, CHB patients were divided into mild (no detectable liver damage) and moderate-to-severe (abnormal liver function) CHB group. This evidence concerns the gene CCL5 and Cirrhosis.