MAPK3 and ovarian cancer: In ovarian cancer cell lines HO-8910PM and ES-2 transfected with the miR-7 plasmid, decreased phosphorylation levels of AKT in Ser473 and ERK1/2 in Thr202/Tyr204, as well as decreased levels of vimentin and increased levels of cytokeratin 18 and β-catenin suggest that miR-7 reversed EMT through the inhibition of AKT and ERK1/2 [191].