To approach the participation of ATP6V0d2 in cholesterol homeostasis, we have evaluated the mRNA levels of scavenger receptors and of the sterol regulatory element-binding protein 2 (SREBP2) which controls expression of genes involved in cholesterol synthesis [51], in the context of ATP6V0d2 knock-down, infection with Leishmania and treatment with ox-LDL. Here, SREBF2 is linked to infection.