CTSD and infection: Subsequently, B. pseudomallei resides, at least in the early phase of infection, in a Rab32-positive compartment, and more importantly, Rab32 promotes the fusion of B. pseudomallei-containing phagosomes with lysosomes that likely result in increased exposure of B. pseudomallei to lysosomal acid hydrolases, CTSD, and enhances the killing of B. pseudomallei by macrophages.