CD101 and type 1 diabetes mellitus: To evaluate the impact of CD101 on T1D, we introgressed the Idd10 and Idd10/Idd18 regions from a B6 CD101 KO strain onto the NOD background and observed that T1D protection mediated by the B6-derived Idd10 and Idd10/Idd18 regions was lost in CD101−/− NOD.B6 Idd10 and CD101−/− NOD.B6 Idd10/Idd18 mice.