By Fisher's exact test, we found a significant association between TMB‐H and multiple gene mutations, including FAT1, TP53, SPTA1, KEAP1, KMT2D, MAGI2, NOTCH2, NOTCH3, FLT1, KDM6A, and FAT4, in the Chinese SCLC patients (Table S3). This evidence concerns the gene NOTCH3 and small cell lung carcinoma.