By Fisher's exact test, we found a significant association between TMB‐H and multiple gene mutations, including FAT1, TP53, SPTA1, KEAP1, KMT2D, MAGI2, NOTCH2, NOTCH3, FLT1, KDM6A, and FAT4, in the Chinese SCLC patients (Table S3). The gene discussed is NOTCH2; the disease is small cell lung carcinoma.