TXNIP and vitamin D deficiency: accumulating evidence from gastric cancer cells, animal models, and clinical trials suggest that vitamin D deficiency may increase the risk and mortality of gastric cancer.37 Vitamin D‐3 upregulated protein 1 (VDUP1) is a potent tumor suppressor whose expression is dramatically reduced in various types of human cancers, including gastric cancer.38 Ample sunshine can provide the body with adequate vitamin D, which can inhibit the risk of stomach cancer.