Previous research showed that Magnolia kobus potently inhibited the lipopolysaccharide‐induced production of TNF‐α and IL‐1β in a murine macrophage‐like cell.30 Our current results indicate that T2D induced significant increases in TNF‐α, IL‐1β, and ICAM expression levels, which were substantially reduced by MH. Here, TNF is linked to type 2 diabetes mellitus.