Two circRNAs with expression upregulation in GC (namely hsa_circ_0008365/circ‐SERPINE2 and hsa_circ_0067127/circ‐ALDH1L1) and the hsa_circ_0000507 (circ‐CUL4A) with expression downregulation in GC were found (Figure 1B). Here, SERPINE2 is linked to gastric cancer.