As shown in Figure 1, EIF3a is highly expressed in various tissues and cancers, and on the other hand, EIF3a could present as both biomarkers and potential anticancer drug target in lung cancer and ovarian cancer.19, 22, 23, 24 Therefore, lung cancer and ovarian cancer will be taken as an example to analyze the impact of EIF3a on the survival of patients who suffered from these cancers. This evidence concerns the gene EIF3A and cancer.