It is interesting to note that an association between Gal‐3 and STAT3 activation was found in pathological‐associated inflammation in the brain.41 It has been demonstrated that extracellular Gal‐3 could amplify the inflammatory cascade in the brain through the rapid induction of STAT3 phosphorylation in monolayer primary glial cell culture.41 It should be emphasized that inflammation plays a key role in ovarian cancer initiation and progression and one could speculate that increased Gal‐3 expression in ovarian cancer MCTS would be through paracrine effects of secreted cytokines by OC cells. The gene discussed is LGALS3; the disease is ovarian carcinoma.