LGALS3 and neoplasm: Galectin‐3 (Gal‐3) is a unique member of galectin family containing a C‐terminal carbohydrate recognition domain, which binds to β‐galactosides and its N‐terminal domain is needed for Gal‐3 enigmatic behavior and cross‐linking activity.5 Changes in Gal‐3 expression are commonly seen in cancer and pre‐cancerous conditions.6 Moreover, Gal‐3 has anti‐ or proapoptotic action depending on its subcellular localization and is involved in cellular proliferation, adhesion, motility, metastasis and thereupon tumor progression.6