A mutation in the promoter region of human KCTD12 was reported to contribute to bipolar I disorder.62 Similarly, elevated protein levels of human KCTD12 were associated with depression63 and schizophrenia.64 Consistent with these findings, kctd12 ‐knockout mice exhibit related phenotypes including altered emotional behaviors and increased neuronal excitability,65 supporting a potential role for KCTD12 in neuropsychiatric disorders. The gene discussed is KCTD12; the disease is bipolar I disorder.