To address this gap, members of the European Society for Paediatric Nephrology (ESPN) CKD-MBD, Dialysis and Transplantation working groups have developed clinical practice recommendations (CPRs) for the use of GH in children with CKD on dialysis and after renal transplantation with input from experts in paediatric nephrology, paediatric endocrinology, pharmacy, epidemiology and patient representatives. The gene discussed is GH1; the disease is chronic kidney disease.