In line with this, primary CLL cells from MYD88-mutated patients analyzed in cell culture supernatants by Luminex® Bead Panel secreted higher levels of CCL2, CCL3, and CCL4 in vitro compared with MYD88-unmutated CLL cases (Fig. 1c, right panel). The gene discussed is CCL4; the disease is B-cell chronic lymphocytic leukemia.