The results with MCF7 cells suggest that growth inhibition from reducing NRAD1 is not exclusive to TN basal-like breast cancers; however, based on the apoptosis results (Fig. 2c), targeting the lncRNA seems less effective in the ER + MCF7 cells with lower levels of NRAD1 expression (Supplemental Fig. 4). The gene discussed is NRAD1; the disease is breast cancer.