AQP3 and neoplasm: In order to explore the mechanism of AQP3 carcinogenesis, the mRNA expression profile of Lv-AQP3-shRNA1-transfected HCCLM3 and HUH7 cells was compared with that of Lv-AQP3-NC transfected cells using a Human Tumor Proliferation/Invasion RT2 ProfilerTM PCR Array containing 86 cell proliferation/metastasis-related genes (Supporting files 1, 2).