Previously mentioned evidence points to ROS-mediated activation of TRPA1 being a major trigger in neuropathic pain; thus antioxidant molecules are being proposed as candidates to treat painful symptoms in neuropathic pain [162,191], such as a blocker of semicarbazide-sensitive amine oxidase (SSAO), TRPA1, and TRPV1 [194]. This evidence concerns the gene TRPA1 and Pain.