GLS and posterior cortical atrophy: Our results showed that the percentage of cells was significantly increased in G0/G1 phase while decreased in G2/M phase when GLS expression was inhibited (Figure 4C,D), indicating that down-regulation of GLS expression could arrest more cells at G0/G1 phase, reduce the ratio of cells at S and G2/M phases, and thus, inhibite the proliferation of PCa cells.