The data obtained from the current study, showed that genotypes GG and AA of IL-17; rs2275913 and IL-1β; rs16944, respectively might be associated with severity of influenza A/H1N1 and B infections but IL-10; rs1800872 and IL-28; rs8099917 SNPs did not show any association with the risk of infection. This evidence concerns the gene IL17A and infection.