Representative western blot images of total spinal cord (post-mortem) tissue lysates from four controls and 10 ALS probed with anti-ERK1 (GTX100699), anti-ERK2 (GTX113094), anti-p90RSK (sc-74459), anti-AKT (sc-271149) and anti-GAPDH (NB-300-285) antibodies. The gene discussed is RPS6KA1; the disease is amyotrophic lateral sclerosis.