The strong increase in the expression levels of the IFN signalling genes (ISGs) observed in DFX-treated healthy HS/PCs was confirmed in the DFX-treated Kasumi-1 and K562 leukemia cell lines irrespective of their different maturation stage (M2 versus M1) or ability to generate different colonies (CFU-GM versus BFU-E). Here, IFNA1 is linked to leukemia.