The methylation status of promoter region of SSTR5-AS1 in LSCC tissues was associated with TNM stage, pathological differentiation, and lymph node metastasis (P < 0.05), while the methylation status of exon 1 of SSTR5-AS1 in LSCC tissues was not associated with any clinicopathologic characteristics (Table 2). The gene discussed is SSTR5; the disease is metastatic malignant neoplasm in the lymph nodes.