EP300 and leukemia: Proscillaridin A induced a rapid loss of MYC protein expression in MYC-driven leukemia cells through the downregulation of series of KATs (KAT2A, KAT3A, KAT3B, KAT5 and KAT6A) known to be involved in MYC protein stability (by lysine acetylation) and activation of MYC transcriptional programs [33, 39–41, 51].